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Document type:
journal article 
Author(s):
Klose, T; Abiatari, I; Samkharadze, T; De Oliveira, T; Jäger, C; Kiladze, M; Valkovskaya, N; Friess, H; Michalski, CW; Kleeff, J 
Title:
The actin binding protein destrin is associated with growth and perineural invasion of pancreatic cancer. 
Abstract:
The small actin-binding protein destrin is one of the key regulators involved in remodeling of the actin cytoskeleton, a process crucial for cytokinesis, cell migration and polarized cell growth as well as for cancer cell migration and invasion.A novel ex vivo nerve invasion model mirroring perineural cancer cell invasion as a key feature of pancreatic ductal adenocarcinoma has been previously established. Using this model, highly nerve-invasive clones of human pancreatic cancer cell lines have...    »
 
Journal title abbreviation:
Pancreatology 
Year:
2012 
Journal volume:
12 
Journal issue:
Pages contribution:
350-7 
Language:
eng 
Print-ISSN:
1424-3903 
TUM Institution:
Chirurgiesche Klinik und Poliklinik