Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Slotta-Huspenina, J; Berg, D; Bauer, K; Wolff, C; Malinowsky, K; Bauer, L; Drecoll, E; Bettstetter, M; Feith, M; Walch, A; Höfler, H; Becker, KF; Langer, R 
Titel:
Evidence of prognostic relevant expression profiles of heat-shock proteins and glucose-regulated proteins in oesophageal adenocarcinomas. 
Abstract:
A high percentage of oesophageal adenocarcinomas show an aggressive clinical behaviour with a significant resistance to chemotherapy. Heat-shock proteins (HSPs) and glucose-regulated proteins (GRPs) are molecular chaperones that play an important role in tumour biology. Recently, novel therapeutic approaches targeting HSP90/GRP94 have been introduced for treating cancer. We performed a comprehensive investigation of HSP and GRP expression including HSP27, phosphorylated (p)-HSP27((Ser15)), p-HSP...    »
 
Zeitschriftentitel:
PLoS ONE 
Jahr:
2012 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
e41420 
Sprache:
eng 
TUM Einrichtung:
r Allgemeine Pathologie und pathologische Anatomie; Chirurgiesche Klinik und Poliklinik