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Dokumenttyp:
journal article 
Autor(en):
Mayer, A; von Wallbrunn, A; Vaupel, P 
Titel:
Evidence against a major role for TKTL-1 in hypoxic and normoxic cancer cells. 
Abstract:
Based on studies performed with a selected mouse monoclonal anti-transketolase- like (TKTL)-1 antibody (clone JFC12T10), overexpression of TKTL-1 has been shown to be correlated with poor survival and increased metastatic spread in several human tumor entities. Since the clinical aggressiveness mediated by TKTL-1 has been partially related to resistance to hypoxia,we originally aimed to explore the influence of hypoxia on the expression of TKTL-1. Unexpectedly, results of our experiments indicat...    »
 
Zeitschriftentitel:
Adv Exp Med Biol 
Jahr:
2011 
Band / Volume:
701 
Seitenangaben Beitrag:
123-8 
Sprache:
eng 
Print-ISSN:
0065-2598 
TUM Einrichtung:
r Strahlentherapie und Radiologische Onkologie