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Dokumenttyp:
journal article 
Autor(en):
Arner, P; Bernard, S; Salehpour, M; Possnert, G; Liebl, J; Steier, P; Buchholz, BA; Eriksson, M; Arner, E; Hauner, H; Skurk, T; Rydén, M; Frayn, KN; Spalding, KL 
Titel:
Dynamics of human adipose lipid turnover in health and metabolic disease. 
Abstract:
Adipose tissue mass is determined by the storage and removal of triglycerides in adipocytes. Little is known, however, about adipose lipid turnover in humans in health and pathology. To study this in vivo, here we determined lipid age by measuring (14)C derived from above ground nuclear bomb tests in adipocyte lipids. We report that during the average ten-year lifespan of human adipocytes, triglycerides are renewed six times. Lipid age is independent of adipocyte size, is very stable across a wi...    »
 
Zeitschriftentitel:
Nature 
Jahr:
2011 
Band / Volume:
478 
Heft / Issue:
7367 
Seitenangaben Beitrag:
110-3 
Sprache:
eng 
Print-ISSN:
0028-0836 
TUM Einrichtung:
hrungsmedizin