Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Eyerich, S; Wagener, J; Wenzel, V; Scarponi, C; Pennino, D; Albanesi, C; Schaller, M; Behrendt, H; Ring, J; Schmidt-Weber, CB; Cavani, A; Mempel, M; Traidl-Hoffmann, C; Eyerich, K 
Titel:
IL-22 and TNF-? represent a key cytokine combination for epidermal integrity during infection with Candida albicans. 
Abstract:
T cells exercise their full impact on target cells through a combination of secreted cytokines. The recently described T helper cell subset Th22 is characterized by a combinatorial secretion of IL-22 and TNF-?. Here, we demonstrate that IL-22 increases the TNF-?-dependent induction and secretion of several immune-modulatory molecules such as initial complement factors C1r and C1s, antimicrobial peptides S100A7 and HBD-2 (human ? defensin 2), and antimicrobial chemokines CXCL-9/-10/-11 in primary...    »
 
Zeitschriftentitel:
Eur J Immunol 
Jahr:
2011 
Band / Volume:
41 
Heft / Issue:
Seitenangaben Beitrag:
1894-901 
Sprache:
eng 
Print-ISSN:
0014-2980 
TUM Einrichtung:
r Molekulare Allergologie und Umweltforschung; r Dermatologie und Allergologie