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Document type:
journal article 
Author(s):
Lindauer, U; Dirnagl, U; Füchtemeier, M; Böttiger, C; Offenhauser, N; Leithner, C; Royl, G 
Title:
Pathophysiological interference with neurovascular coupling - when imaging based on hemoglobin might go blind. 
Abstract:
Assessing neuronal activity by non-invasive functional brain imaging techniques which are based on the hemodynamic response depends totally on the physiological cascade of metabolism and blood flow. At present, functional brain imaging with near infrared spectroscopy (NIRS) or BOLD-fMRI is widely used in cognitive neuroscience in healthy subjects where neurovascular coupling and cerebrovascular reactivity can be assumed to be intact. Local activation studies as well as studies investigating func...    »
 
Journal title abbreviation:
Front Neuroenergetics 
Year:
2010 
Journal volume:
Language:
eng 
TUM Institution:
Neurochirurgische Klinik und Poliklinik