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Dokumenttyp:
journal article 
Autor(en):
Ingold, B; Simon, E; Ungethüm, U; Kuban, RJ; Müller, BM; Lupp, A; Neumann, U; Ebert, MP; Denkert, C; Weichert, W; Schulz, S; Röcken, C 
Titel:
Vascular CXCR4 expression - a novel antiangiogenic target in gastric cancer? 
Abstract:
G-protein-coupled receptors (GPCRs) are prime candidates for novel cancer prevention and treatment strategies. We searched for differentially expressed GPCRs in node positive gastric carcinomas.Differential expression of GPCRs in three node positive vs. three node negative intestinal type gastric carcinomas was analyzed by gene array technology. The candidate genes CXCL12 and its receptor CXCR4 were validated by real-time reverse-transcription polymerase chain reaction in an independent set of 3...    »
 
Zeitschriftentitel:
PLoS ONE 
Jahr:
2010 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
e10087 
Sprache:
eng 
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik