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Document type:
journal article 
Author(s):
Bültmann, A; Li, Z; Wagner, S; Peluso, M; Schönberger, T; Weis, C; Konrad, I; Stellos, K; Massberg, S; Nieswandt, B; Gawaz, M; Ungerer, M; Münch, G 
Title:
Impact of glycoprotein VI and platelet adhesion on atherosclerosis--a possible role of fibronectin. 
Abstract:
Glycoprotein VI (GPVI) mediates binding of platelets to subendothelial collagen during acute arterial thrombosis. GPVI interactions with the activated atherosclerotic vascular endothelium during early atherosclerosis, however, are not well understood. In ApoE-/- mice, platelet adhesion to atherosclerotic arteries was increased, as measured by intravital microscopy. This platelet adhesion was significantly inhibited by IV injection of GPVI-Fc (1 mg/kg body weight). Atherosclerosis in ApoE-/- mice...    »
 
Journal title abbreviation:
J Mol Cell Cardiol 
Year:
2010 
Journal volume:
49 
Journal issue:
Pages contribution:
532-42 
Language:
eng 
Print-ISSN:
0022-2828 
TUM Institution:
I. Medizinische Klinik und Poliklinik