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Dokumenttyp:
journal article 
Autor(en):
Bültmann, A; Li, Z; Wagner, S; Peluso, M; Schönberger, T; Weis, C; Konrad, I; Stellos, K; Massberg, S; Nieswandt, B; Gawaz, M; Ungerer, M; Münch, G 
Titel:
Impact of glycoprotein VI and platelet adhesion on atherosclerosis--a possible role of fibronectin. 
Abstract:
Glycoprotein VI (GPVI) mediates binding of platelets to subendothelial collagen during acute arterial thrombosis. GPVI interactions with the activated atherosclerotic vascular endothelium during early atherosclerosis, however, are not well understood. In ApoE-/- mice, platelet adhesion to atherosclerotic arteries was increased, as measured by intravital microscopy. This platelet adhesion was significantly inhibited by IV injection of GPVI-Fc (1 mg/kg body weight). Atherosclerosis in ApoE-/- mice...    »
 
Zeitschriftentitel:
J Mol Cell Cardiol 
Jahr:
2010 
Band / Volume:
49 
Heft / Issue:
Seitenangaben Beitrag:
532-42 
Sprache:
eng 
Print-ISSN:
0022-2828 
TUM Einrichtung:
I. Medizinische Klinik und Poliklinik