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Dokumenttyp:
journal article 
Autor(en):
Marquardt, JU; Quasdorff, M; Varnholt, H; Curth, HM; Mesghenna, S; Protzer, U; Goeser, T; Nierhoff, D 
Titel:
Neighbor of punc E11, a novel oncofetal marker for hepatocellular carcinoma. 
Abstract:
Hepatocellular carcinoma (HCC) is the 5th common malignancy worldwide, but established markers fail to detect up to one third of HCC. We have recently identified Neighbor of Punc E11 (Nope) as a surface marker for murine fetal liver stem cells. Similar to commonly used HCC markers such as ?-Fetoprotein (Afp) and Glypican-3 (Gpc-3), we here establish Nope as an oncofetal marker of murine and human HCC and investigate its specific expression in hepatoma cell lines and primary HCC. Murine and human...    »
 
Zeitschriftentitel:
Int J Cancer 
Jahr:
2011 
Band / Volume:
128 
Heft / Issue:
10 
Seitenangaben Beitrag:
2353-63 
Sprache:
eng 
Print-ISSN:
0020-7136 
TUM Einrichtung:
r Virologie