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Document type:
journal article 
Author(s):
Quasdorff, M; Protzer, U 
Title:
Control of hepatitis B virus at the level of transcription. 
Abstract:
Hepatitis B virus (HBV) is tightly controlled by a number of noncytotoxic mechanisms. This control occurs within the host hepatocyte at different steps of the HBV replication cycle. HBV persists by establishing a nuclear minichromosome, HBV cccDNA, serving as a transcription template for the viral pregenome and viral mRNAs. Nucleoside/nucleotide analogues widely used for antiviral therapy as well as most antiviral cytokines act at steps after transcription of HBV RNAs and thus can control virus...    »
 
Journal title abbreviation:
J Viral Hepat 
Year:
2010 
Journal volume:
17 
Journal issue:
Pages contribution:
527-36 
Language:
eng 
Print-ISSN:
1352-0504 
TUM Institution:
Institut für Virologie