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Dokumenttyp:
journal article 
Autor(en):
Stabenow, D; Frings, M; Trück, C; Gärtner, K; Förster, I; Kurts, C; Tüting, T; Odenthal, M; Dienes, HP; Cederbrant, K; Protzer, U; Knolle, PA 
Titel:
Bioluminescence imaging allows measuring CD8 T cell function in the liver. 
Abstract:
In vivo evaluation of CD8 T cell effector (cytotoxic T lymphocyte [CTL]) function in peripheral organs such as the liver is currently not possible but would greatly improve our understanding of local immune regulation, because simple determination of antigen-specific CTL numbers does not predict the outcome of immune responses. In particular, measurement of alanine aminotransferase serum levels is not sensitive enough to detect T cell immunity against low numbers of target hepatocytes. We develo...    »
 
Zeitschriftentitel:
Hepatology 
Jahr:
2010 
Band / Volume:
51 
Heft / Issue:
Seitenangaben Beitrag:
1430-7 
Sprache:
eng 
Print-ISSN:
0270-9139 
TUM Einrichtung:
r Virologie