Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Schulz, U; Kreutz, M; Multhoff, G; Stoelcker, B; Köhler, M; Andreesen, R; Holler, E 
Titel:
Interleukin-10 promotes NK cell killing of autologous macrophages by stimulating expression of NKG2D ligands. 
Abstract:
Under inflammatory conditions, the pleiotropic cytokine interleukin-10 (IL-10) is released in many tissues. It mediates anti-inflammatory effects in particular by inhibiting the release of T helper type 1 (Th1) cytokines. In contrast, we show here that NK cell cytotoxicity against autologous macrophages is elevated if both cell types are cultured with IL-10. The expression of most activatory NK receptors is increased after culture in the presence of IL-10. On the other hand, macrophages cultured...    »
 
Zeitschriftentitel:
Scand J Immunol 
Jahr:
2010 
Band / Volume:
72 
Heft / Issue:
Seitenangaben Beitrag:
319-31 
Sprache:
eng 
Print-ISSN:
0300-9475 
TUM Einrichtung:
r Strahlentherapie und Radiologische Onkologie