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Dokumenttyp:
journal article 
Autor(en):
Edelmann, F; Schmidt, AG; Gelbrich, G; Binder, L; Herrmann-Lingen, C; Halle, M; Hasenfuss, G; Wachter, R; Pieske, B 
Titel:
Rationale and design of the'aldosterone receptor blockade in diastolic heart failure' trial: a double-blind, randomized, placebo-controlled, parallel group study to determine the effects of spironolactone on exercise capacity and diastolic function in pa 
Abstract:
Increasing evidence suggests that enhanced aldosterone signalling plays a key role in the onset and progression of diastolic heart failure (DHF). Aldo-DHF will test the hypothesis that aldosterone receptor blockade by spironolactone will improve exercise capacity and diastolic function in patients with DHF.Aldo-DHF is a randomized, placebo-controlled, double-blinded, two-armed, multicentre, parallel group study. Four hundred and twenty patients with DHF will be randomly assigned to receive spiro...    »
 
Zeitschriftentitel:
Eur J Heart Fail 
Jahr:
2010 
Band / Volume:
12 
Heft / Issue:
Seitenangaben Beitrag:
874-82 
Sprache:
eng 
Print-ISSN:
1388-9842 
TUM Einrichtung:
ventive und rehabilitative Sportmedizin