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Document type:
journal article 
Author(s):
Winter, S; Loddenkemper, C; Aebischer, A; Räbel, K; Hoffmann, K; Meyer, TF; Lipp, M; Höpken, UE 
Title:
The chemokine receptor CXCR5 is pivotal for ectopic mucosa-associated lymphoid tissue neogenesis in chronic Helicobacter pylori-induced inflammation. 
Abstract:
Ectopic lymphoid follicles are a key feature of chronic inflammatory autoimmune and infectious diseases, such as rheumatoid arthritis, Sjögren's syndrome, and Helicobacter pylori-induced gastritis. Homeostatic chemokines are considered to be involved in the formation of such tertiary lymphoid tissue. High expression of CXCL13 and its receptor, CXCR5, has been associated with the formation of ectopic lymphoid follicles in chronic infectious diseases. Here, we defined the role of CXCR5 in the deve...    »
 
Journal title abbreviation:
J Mol Med 
Year:
2010 
Journal volume:
88 
Journal issue:
11 
Pages contribution:
1169-80 
Language:
eng 
Print-ISSN:
0946-2716 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie