Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Schulte, EC; Sauerbrei, A; Hoffmann, D; Zimmer, C; Hemmer, B; Mühlau, M 
Titel:
Acyclovir resistance in herpes simplex encephalitis. 
Abstract:
Herpes simplex virus type 1 is a common cause of severe sporadic encephalitis. Treatment with acyclovir is highly effective in this disease. We report the case of a 27-year-old, immunocompetent woman with acyclovir-resistant herpes simplex encephalitis. Although she had not been treated before, herpes simplex virus type 1 DNA from the cerebrospinal fluid showed a non-synonymous mutation in the thymidine kinase gene, which is likely to have caused resistance to acyclovir. Herpes simplex encephali...    »
 
Zeitschriftentitel:
Ann Neurol 
Jahr:
2010 
Band / Volume:
67 
Heft / Issue:
Seitenangaben Beitrag:
830-3 
Sprache:
eng 
Print-ISSN:
0364-5134 
TUM Einrichtung:
Neurologische Klinik und Poliklinik; r Neuroradiologie