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Dokumenttyp:
journal article 
Autor(en):
Rusai, K; Prókai, A; Szebeni, B; Fekete, A; Treszl, A; Vannay, A; Müller, V; Reusz, G; Heemann, U; Lutz, J; Tulassay, T; Szabó, AJ 
Titel:
Role of serum and glucocorticoid-regulated kinase-1 in the protective effects of erythropoietin during renal ischemia/reperfusion injury. 
Abstract:
Erythropoietin (EPO) protects the kidneys from ischemia/reperfusion (I/R) injury; however, the exact signalling mechanisms are not fully understood. The serum and glucocorticoid-regulated kinase 1 (SGK1) is an anti-apoptotic protein kinase regulated through the phosphatidylinositol 3-kinase (PI3-kinase) pathway by cellular stimuli, hormones and growth factors. The objective of the present study was to examine the role of SGK1 in the renoprotective effects of EPO in renal I/R injury. In vitro, c...    »
 
Zeitschriftentitel:
Biochem Pharmacol 
Jahr:
2010 
Band / Volume:
79 
Heft / Issue:
Seitenangaben Beitrag:
1173-81 
Sprache:
eng 
Print-ISSN:
0006-2952 
TUM Einrichtung:
r Nephrologie