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Dokumenttyp:
journal article 
Autor(en):
Layland, LE; Mages, J; Loddenkemper, C; Hoerauf, A; Wagner, H; Lang, R; da Costa, CU 
Titel:
Pronounced phenotype in activated regulatory T cells during a chronic helminth infection. 
Abstract:
Although several markers have been associated with the characterization of regulatory T cells (Tregs) and their function, no studies have investigated the dynamics of their phenotype during infection. Since the necessity of Tregs to control immunopathology has been demonstrated, we used the chronic helminth infection model Schistosoma mansoni to address the impact on the Treg gene repertoire. Before gene expression profiling, we first studied the localization and Ag-specific suppressive nature o...    »
 
Zeitschriftentitel:
J Immunol 
Jahr:
2010 
Band / Volume:
184 
Heft / Issue:
Seitenangaben Beitrag:
713-24 
Sprache:
eng 
Print-ISSN:
0022-1767 
TUM Einrichtung:
r Medizinische Mikrobiologie, Immunologie und Hygiene