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Dokumenttyp:
journal article 
Autor(en):
Bonifacio, E; Ziegler, AG 
Titel:
Advances in the prediction and natural history of type 1 diabetes. 
Abstract:
Type 1 diabetes (T1D) has the hallmark characteristics of autoimmunity superimposed on genetic susceptibility. Both genes (HLA) and immune markers (autoantibodies) have been validated as predictive markers of the subsequent development of the disease in higher-risk relatives and the lower-risk general population. Over the last three decades, using a combination of genes, immune, and metabolic markers, clinicians are now able to quantify an individual's disease risk from 1 in 100,000 to more than...    »
 
Zeitschriftentitel:
Endocrinol Metab Clin North Am 
Jahr:
2010 
Band / Volume:
39 
Heft / Issue:
Seitenangaben Beitrag:
513-25 
Sprache:
eng 
Print-ISSN:
0889-8529 
TUM Einrichtung:
Kinderklinik und Poliklinik