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Document type:
journal article 
Author(s):
Kremser, A; Dressig, J; Grabrucker, C; Liepert, A; Kroell, T; Scholl, N; Schmid, C; Tischer, J; Kufner, S; Salih, H; Kolb, HJ; Schmetzer, H 
Title:
Dendritic cells (DCs) can be successfully generated from leukemic blasts in individual patients with AML or MDS: an evaluation of different methods. 
Abstract:
Myeloid-leukemic cells (AML, MDS, CML) can be differentiated to leukemia-derived dendritic cell [DC (DCleu)] potentially presenting the whole leukemic antigen repertoire without knowledge of distinct leukemia antigens and are regarded as promising candidates for a vaccination strategy. We studied the capability of 6 serum-free DC culture methods, chosen according to different mechanisms, to induce DC differentiation in 137 cases of AML and 52 cases of MDS. DC-stimulating substances were cytokine...    »
 
Journal title abbreviation:
J Immunother 
Year:
2010 
Journal volume:
33 
Journal issue:
Pages contribution:
185-99 
Language:
eng 
Print-ISSN:
1524-9557 
TUM Institution:
III. Medizinische Klinik und Poliklinik