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Dokumenttyp:
journal article 
Autor(en):
Keller, U; Huber, J; Nilsson, JA; Fallahi, M; Hall, MA; Peschel, C; Cleveland, JL 
Titel:
Myc suppression of Nfkb2 accelerates lymphomagenesis. 
Abstract:
Deregulated c-Myc expression is a hallmark of several human cancers where it promotes proliferation and an aggressive tumour phenotype. Myc overexpression is associated with reduced activity of Rel/NF-kappaB, transcription factors that control the immune response, cell survival, and transformation, and that are frequently altered in cancer. The Rel/NF-kappaB family member NFKB2 is altered by chromosomal translocations or deletions in lymphoid malignancies and deletion of the C-terminal ankyrin d...    »
 
Zeitschriftentitel:
BMC Cancer 
Jahr:
2010 
Band / Volume:
10 
Seitenangaben Beitrag:
348 
Sprache:
eng 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik