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Dokumenttyp:
journal article 
Autor(en):
Lordick, F; Luber, B; Lorenzen, S; Hegewisch-Becker, S; Folprecht, G; Wöll, E; Decker, T; Endlicher, E; Röthling, N; Schuster, T; Keller, G; Fend, F; Peschel, C 
Titel:
Cetuximab plus oxaliplatin/leucovorin/5-fluorouracil in first-line metastatic gastric cancer: a phase II study of the Arbeitsgemeinschaft Internistische Onkologie (AIO). 
Abstract:
BACKGROUND: Cetuximab enhances the efficacy of chemotherapy in several cancer types. This trial assessed the activity of cetuximab and chemotherapy in advanced gastric cancer. METHODS: Patients with previously untreated, metastatic, gastric cancer received cetuximab 400 mg m(-2) at first infusion followed by weekly infusions of 250 mg m(-2) combined with FUFOX (oxaliplatin 50 mg m(-2), 5-FU 2000 mg m(-2), and DL-folinic acid 200 mg m(-2) d1, 8, 15 and 22 qd36). The primary endpoint was tumour re...    »
 
Zeitschriftentitel:
Br J Cancer 
Jahr:
2010 
Band / Volume:
102 
Heft / Issue:
Seitenangaben Beitrag:
500-5 
Sprache:
eng 
Print-ISSN:
0007-0920 
TUM Einrichtung:
r Allgemeine Pathologie und pathologische Anatomie; III. Medizinische Klinik und Poliklinik; r Medizinische Statistik und Epidemiologie