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Dokumenttyp:
journal article 
Autor(en):
Bas, M; Greve, J; Stelter, K; Bier, H; Stark, T; Hoffmann, TK; Kojda, G 
Titel:
Therapeutic efficacy of icatibant in angioedema induced by angiotensin-converting enzyme inhibitors: a case series. 
Abstract:
The pathophysiology of angiotensin-converting enzyme inhibitor (ACEi)-induced angioedema most likely resembles that of hereditary angioedema, ie, it is mainly mediated by bradykinin-induced activation of vascular bradykinin B2 receptors. We hypothesize that the bradykinin B2 receptor antagonist icatibant might be an effective therapy for ACEi-induced angioedema.Eight patients with acute ACEi-induced angioedema were treated with a single subcutaneous injection of icatibant. The outcome was assess...    »
 
Zeitschriftentitel:
Ann Emerg Med 
Jahr:
2010 
Band / Volume:
56 
Heft / Issue:
Seitenangaben Beitrag:
278-82 
Sprache:
eng 
Print-ISSN:
0196-0644 
TUM Einrichtung:
Hals-, Nasen-, Ohrenklinik und Poliklinik