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Dokumenttyp:
journal article 
Autor(en):
Reckhenrich, AK; Hopfner, U; Krötz, F; Zhang, Z; Koch, C; Kremer, M; Machens, HG; Plank, C; Egaña, JT 
Titel:
Bioactivation of dermal scaffolds with a non-viral copolymer-protected gene vector. 
Abstract:
The use of scaffolds in skin tissue engineering is accompanied with low regeneration rates and high risk of infection. In this study, we activated an FDA-approved collagen scaffold for dermal regeneration by incorporation of copolymer-protected gene vectors (COPROGs) to induce a temporary release of VEGF. In vitro results show that the presence of COPROGs did not affect the distribution, attachment, proliferation and viability of cells in the scaffold. A transient release of VEGF was observed fo...    »
 
Zeitschriftentitel:
Biomaterials 
Jahr:
2011 
Band / Volume:
32 
Heft / Issue:
Seitenangaben Beitrag:
1996-2003 
Sprache:
eng 
Print-ISSN:
0142-9612 
TUM Einrichtung:
r Plastische Chirurgie und Handchirurgie; r experimentelle Onkologie und Therapieforschung