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Dokumenttyp:
journal article 
Autor(en):
Omlor, GW; Bertram, H; Kleinschmidt, K; Fischer, J; Brohm, K; Guehring, T; Anton, M; Richter, W 
Titel:
Methods to monitor distribution and metabolic activity of mesenchymal stem cells following in vivo injection into nucleotomized porcine intervertebral discs. 
Abstract:
Intervertebral disc (IVD) degeneration involves a series of biochemical and morphological changes leading to loss of spinal stability and flexibility. Cell therapy is promising to reconstitute IVDs with new cells, however, sustained metabolic activity seems crucial for an active contribution to regeneration. The aim of the present study was to establish methods for separate follow up of persistence and activity of autologous porcine mesenchymal stem cells (pMSC) after implantation into IVDs of G...    »
 
Zeitschriftentitel:
Eur Spine J 
Jahr:
2010 
Band / Volume:
19 
Heft / Issue:
Seitenangaben Beitrag:
601-12 
Sprache:
eng 
Print-ISSN:
0940-6719 
TUM Einrichtung:
r experimentelle Onkologie und Therapieforschung