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Dokumenttyp:
journal article 
Autor(en):
Loos, M; Hedderich, DM; Friess, H; Kleeff, J 
Titel:
B7-h3 and its role in antitumor immunity. 
Abstract:
B7-H3 is one of the most recently identified members of the B7/CD28 superfamily of costimulatory molecules serving as an accessory modulator of T-cell response. Recently, B7-H3 expression has been reported in several human cancers indicating an additional function of B7-H3 as a regulator of antitumor immunity. However, its precise physiologic role is still elusive, because both stimulatory and inhibitory capacities have been demonstrated. This paper summarizes the available data on B7-H3 in the...    »
 
Zeitschriftentitel:
Clin Dev Immunol 
Jahr:
2010 
Band / Volume:
2010 
Seitenangaben Beitrag:
683875 
Sprache:
eng 
Print-ISSN:
1740-2522 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik