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Dokumenttyp:
journal article 
Autor(en):
Ceyhan, GO; Liebl, F; Maak, M; Schuster, T; Becker, K; Langer, R; Demir, IE; Hartel, M; Friess, H; Rosenberg, R 
Titel:
The severity of neural invasion is a crucial prognostic factor in rectal cancer independent of neoadjuvant radiochemotherapy. 
Abstract:
OBJECTIVE: To provide a comprehensive characterization of neural invasion (NI) in rectal adenocarcinoma (RC), to establish a novel NI-severity scoring system, and to assess the prognostic value of NI with emphasis on its localization and severity. BACKGROUND: The literature merely contains small-scale studies with limited histopathological characterization of NI in RC. METHODS: Neural invasion was thoroughly characterized in 296 patients with locally advanced uT3-RC (139 with primary resection a...    »
 
Zeitschriftentitel:
Ann Surg 
Jahr:
2010 
Band / Volume:
252 
Heft / Issue:
Seitenangaben Beitrag:
797-804 
Sprache:
eng 
Print-ISSN:
0003-4932 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik; r Medizinische Statistik und Epidemiologie; r Allgemeine Pathologie und pathologische Anatomie