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Dokumenttyp:
journal article 
Autor(en):
Langer, R; Mutze, K; Becker, K; Feith, M; Ott, K; Höfler, H; Keller, G 
Titel:
Expression of class I histone deacetylases (HDAC1 and HDAC2) in oesophageal adenocarcinomas: an immunohistochemical study. 
Abstract:
BACKGROUND: Histone deacetylases (HDACs) are enzymes which play a central role in post-translational histone and non-histone protein modification. Deregulation of HDACs has been detected in various human malignancies and may also influence response to chemotherapy. AIMS: To investigate the expression of class I histone deacetylase (HDAC) isoforms 1 and 2 in oesophageal adenocarcinomas. METHODS: 132 primary resected tumours and 48 tumours treated by chemotherapy were analysed. Expression of HDAC1...    »
 
Zeitschriftentitel:
J Clin Pathol 
Jahr:
2010 
Band / Volume:
63 
Heft / Issue:
11 
Seitenangaben Beitrag:
994-8 
Sprache:
eng 
Print-ISSN:
0021-9746 
TUM Einrichtung:
r Allgemeine Pathologie und pathologische Anatomie; Chirurgiesche Klinik und Poliklinik