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Dokumenttyp:
journal article 
Autor(en):
Löhr, JM; Faissner, R; Koczan, D; Bewerunge, P; Bassi, C; Brors, B; Eils, R; Frulloni, L; Funk, A; Halangk, W; Jesnowski, R; Kaderali, L; Kleeff, J; Krüger, B; Lerch, MM; Lösel, R; Magnani, M; Neumaier, M; Nittka, S; Sahin-Tóth, M; Sänger, J; Serafini, S; Schnölzer, M; Thierse, HJ; Wandschneider, S; Zamboni, G; Klöppel, G 
Titel:
Autoantibodies against the exocrine pancreas in autoimmune pancreatitis: gene and protein expression profiling and immunoassays identify pancreatic enzymes as a major target of the inflammatory process. 
Abstract:
OBJECTIVES: Autoimmune pancreatitis (AIP) is thought to be an immune-mediated inflammatory process, directed against the epithelial components of the pancreas. The objective was to identify novel markers of disease and to unravel the pathogenesis of AIP. METHODS :To explore key targets of the inflammatory process, we analyzed the expression of proteins at the RNA and protein level using genomics and proteomics, immunohistochemistry, western blot, and immunoassay. An animal model of AIP with LP-B...    »
 
Zeitschriftentitel:
Am J Gastroenterol 
Jahr:
2010 
Band / Volume:
105 
Heft / Issue:
Seitenangaben Beitrag:
2060-71 
Sprache:
eng 
Print-ISSN:
0002-9270 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik; r Allgemeine Pathologie und pathologische Anatomie