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Document type:
journal article 
Author(s):
Ma, Xiaopeng; Phi Van, Valerie; Kimm, Melanie A; Prakash, Jaya; Kessler, Horst; Kosanke, Katja; Feuchtinger, Annette; Aichler, Michaela; Gupta, Aayush; Rummeny, Ernst J; Eisenblätter, Michel; Siveke, Jens; Walch, Axel K; Braren, Rickmer; Ntziachristos, Vasilis; Wildgruber, Moritz 
Title:
Integrin-Targeted Hybrid Fluorescence Molecular Tomography/X-ray Computed Tomography for Imaging Tumor Progression and Early Response in Non-Small Cell Lung Cancer. 
Abstract:
Integrins play an important role in tumor progression, invasion and metastasis. Therefore we aimed to evaluate a preclinical imaging approach applying ???3 integrin targeted hybrid Fluorescence Molecular Tomography/X-ray Computed Tomography (FMT-XCT) for monitoring tumor progression as well as early therapy response in a syngeneic murine Non-Small Cell Lung Cancer (NSCLC) model. Lewis Lung Carcinomas were grown orthotopically in C57BL/6 J mice and imaged in-vivo using a ???3 targeted near-infrar...    »
 
Journal title abbreviation:
Neoplasia 
Year:
2017 
Journal volume:
19 
Journal issue:
Pages contribution:
8-16 
Language:
eng 
Print-ISSN:
1522-8002 
TUM Institution:
Lehrstuhl für Biologische Bildgebung (Prof. Ntziachristos); Institut für Diagnostische und Interventionelle Radiologie; Klinik und Poliklinik für Innere Medizin II