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Document type:
journal article 
Author(s):
Tjalma, Jolien J; Garcia-Allende, P Beatriz; Hartmans, Elmire; Terwisscha van Scheltinga, Anton G; Boersma-van Ek, Wytske; Glatz, Jürgen; Koch, Maximilian; van Herwaarden, Yasmijn J; Bisseling, Tanya M; Nagtegaal, Iris D; Timmer-Bosscha, Hetty; Koornstra, Jan Jacob; Karrenbeld, Arend; Kleibeuker, Jan H; van Dam, Gooitzen M; Ntziachristos, Vasilis; Nagengast, Wouter B 
Title:
Molecular Fluorescence Endoscopy Targeting Vascular Endothelial Growth Factor A for Improved Colorectal Polyp Detection. 
Abstract:
Small and flat adenomas are known to carry a high miss-rate during standard white-light endoscopy. Increased detection rate may be achieved by molecular fluorescence endoscopy with targeted near-infrared (NIR) fluorescent tracers. The aim of this study was to validate vascular endothelial growth factor A (VEGF-A) and epidermal growth factor receptor (EGFR)-targeted fluorescent tracers during ex vivo colonoscopy with an NIR endoscopy platform.VEGF-A and EGFR expression was determined by immunohis...    »
 
Journal title abbreviation:
J Nucl Med 
Year:
2016 
Journal volume:
57 
Journal issue:
Pages contribution:
480-5 
Language:
eng 
Print-ISSN:
0161-5505 
TUM Institution:
Lehrstuhl für Biologische Bildgebung