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Document type:
journal article 
Author(s):
Deán-Ben, X Luís; Buehler, Andreas; Razansky, Daniel; Ntziachristos, Vasilis 
Title:
Estimation of optoacoustic contrast agent concentration with self-calibration blind logarithmic unmixing. 
Abstract:
Chromophore quantification in optoacoustic tomography is challenging due to signal contributions from strongly absorbing background tissue chromophores and the depth-dependent light attenuation. Herein we present a procedure capable of correcting for wavelength-dependent light fluence variations using a logarithmic representation of the images taken at different wavelengths assisted with a blind unmixing approach. It is shown that the serial expansion of the logarithm of an optoacoustic image co...    »
 
Journal title abbreviation:
Phys Med Biol 
Year:
2014 
Journal volume:
59 
Journal issue:
17 
Pages contribution:
4785-97 
Language:
eng 
Print-ISSN:
0031-9155 
TUM Institution:
Lehrstuhl für Biologische Bildgebung