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Document type:
journal article 
Author(s):
Aichler, Michaela; Huber, Katharina; Schilling, Franz; Lohöfer, Fabian; Kosanke, Katja; Meier, Reinhard; Rummeny, Ernst J; Walch, Axel; Wildgruber, Moritz 
Title:
Spatially resolved quantification of gadolinium(III)-based magnetic resonance agents in tissue by MALDI imaging mass spectrometry after in vivo MRI. 
Abstract:
Gadolinium(III)-based contrast agents improve the sensitivity and specificity of magnetic resonance imaging (MRI), especially when targeted contrast agents are applied. Because of nonlinear correlation between the contrast agent concentration in tissue and the MRI signal obtained in vivo, quantification of certain biological or pathophysiological processes by MRI remains a challenge. Up to now, no technology has been able to provide a spatially resolved quantification of MRI agents directly with...    »
 
Journal title abbreviation:
Angew Chem Int Ed Engl 
Year:
2015 
Journal volume:
54 
Journal issue:
14 
Pages contribution:
4279-83 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
0570-0833 
TUM Institution:
Institut für Radiologie; Nuklearmedizinische Klinik und Poliklinik