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Document type:
journal article 
Author(s):
Rochefort, NL; Garaschuk, O; Milos, RI; Narushima, M; Marandi, N; Pichler, B; Kovalchuk, Y; Konnerth, A 
Title:
Sparsification of neuronal activity in the visual cortex at eye-opening. 
Abstract:
Eye-opening represents a turning point in the function of the visual cortex. Before eye-opening, the visual cortex is largely devoid of sensory inputs and neuronal activities are generated intrinsically. After eye-opening, the cortex starts to integrate visual information. Here we used in vivo two-photon calcium imaging to explore the developmental changes of the mouse visual cortex by analyzing the ongoing spontaneous activity. We found that before eye-opening, the activity of layer 2/3 neurons...    »
 
Journal title abbreviation:
Proc Natl Acad Sci U S A 
Year:
2009 
Journal volume:
106 
Journal issue:
35 
Pages contribution:
15049-54 
Language:
eng 
Print-ISSN:
0027-8424 
TUM Institution:
Institut für Neurowissenschaften