User: Guest  Login
Document type:
journal article 
Author(s):
Orlando, C; Castellani, S; Mykhaylyk, O; Copreni, E; Zelphati, O; Plank, C; Conese, M 
Title:
Magnetically guided lentiviral-mediated transduction of airway epithelial cells. 
Abstract:
Lentiviral (LV) vectors are able to only slowly and inefficiently transduce nondividing cells such as those of the airway epithelium. To address this issue, we have exploited the magnetofection technique in in vitro models of airway epithelium.Magnetofectins were formed by noncovalent interaction between LV particles and polycation-coated iron oxide nanoparticles. Efficiency of LV-mediated transduction (as evaluated through green fluorescent protein (GFP) expression by cytofluorimetric analysis)...    »
 
Journal title abbreviation:
J Gene Med 
Year:
2010 
Journal volume:
12 
Journal issue:
Pages contribution:
747-54 
Language:
eng 
Print-ISSN:
1099-498X 
TUM Institution:
Institut für experimentelle Onkologie und Therapieforschung