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Document type:
journal article 
Author(s):
Specht, K; Harbeck, N; Smida, J; Annecke, K; Reich, U; Naehrig, J; Langer, R; Mages, J; Busch, R; Kruse, E; Klein-Hitpass, L; Schmitt, M; Kiechle, M; Hoefler, H 
Title:
Expression profiling identifies genes that predict recurrence of breast cancer after adjuvant CMF-based chemotherapy. 
Abstract:
Cyclophosphamide, methotrexate and 5-fluorouracile (CMF)-based chemotherapy for adjuvant treatment of breast cancer reduces the risk of relapse. In this exploratory study, we tested the feasibility of identifying molecular markers of recurrence in CMF-treated patients. Using Affymetrix U133A GeneChips, RNA samples from 19 patients with primary breast cancer who had been uniformly treated with adjuvant CMF chemotherapy were analyzed. Two supervised class prediction approaches were used to identif...    »
 
Journal title abbreviation:
Breast Cancer Res Treat 
Year:
2009 
Journal volume:
118 
Journal issue:
Pages contribution:
45-56 
Language:
eng 
Print-ISSN:
0167-6806 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie ; Frauenklinik und Poliklinik ; Institut für Medizinische Mikrobiologie, Immunologie und Hygiene ; Institut für Medizinische Statistik und Epidemiologie