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Document type:
journal article 
Author(s):
Bogner, V; Keil, L; Kanz, KG; Kirchhoff, C; Leidel, BA; Mutschler, W; Biberthaler, P 
Title:
Very early posttraumatic serum alterations are significantly associated to initial massive RBC substitution, injury severity, multiple organ failure and adverse clinical outcome in multiple injured patients. 
Abstract:
BACKGROUND: Multiple severe trauma frequently leads to massive dysbalances of the human immune system. This phenomenon is known as "Systemic Inflammatory Response Syndrome (SIRS)". SIRS is connected to multiple organ failure and thereby entails higher morbidity and mortality in trauma patients. Pro- and anti-inflammatory cytokines such as Il-6, Il-8 and Il-10 seem to play a superior role in the development of SIRS. Several studies support the hypothesis that the very early cytokine release patte...    »
 
Journal title abbreviation:
Eur J Med Res 
Year:
2009 
Journal volume:
14 
Journal issue:
Pages contribution:
284-91 
Language:
eng 
Print-ISSN:
0949-2321 
TUM Institution:
die