User: Guest  Login
Document type:
In Vitro; Journal Article; Research Support, Non-U.S. Gov't; Proceedings Paper
Author(s):
Feidt, DM; Klein, K; Nüssler, A; Zanger, UM
Title:
RNA-interference approach to study functions of NADPH : cytochrome P450 oxidoreductase in human hepatocytes.
Abstract:
Human NADPH : cytochrome P450 oxidoreductase (POR) is encoded by a single gene on chromosome 7q11.2. This flavoprotein donates electrons derived from NADPH to a variety of acceptor proteins, including squalene monooxygenase, heme oxygenase, cytochrome b(5), and many microsomal cytochromes P450 (CYPs), which are involved in oxidative drug metabolism, steroidogenesis, and other functions. Numerous aspects related to cellular POR expression have not been systematically investigated. Interestingly,...     »
Journal title abbreviation:
Chem Biodivers
Year:
2009
Journal volume:
6
Journal issue:
11
Pages contribution:
2084-91
Fulltext / DOI:
doi:10.1002/cbdv.200900135
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19937842
Print-ISSN:
1612-1872
TUM Institution:
Klinik und Poliklinik für Unfallchirurgie
 BibTeX