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Document type:
journal article 
Author(s):
Grimmer, T; Henriksen, G; Wester, HJ; Förstl, H; Klunk, WE; Mathis, CA; Kurz, A; Drzezga, A 
Title:
Clinical severity of Alzheimer's disease is associated with PIB uptake in PET. 
Abstract:
BACKGROUND: The positron emission tomography (PET) tracer [11C]-Pittsburgh Compound-B ([11C]PIB) allows the in vivo assessment of amyloid plaque burden in the brain. In a cross-sectional study we examined the association between the severity of dementia assessed using the Clinical Dementia Rating scale sum of boxes (CDR-SOB) and [11C]PIB-PET in patients with Alzheimer's disease (AD). METHODS: Patients with probable AD who had an AD-typical [18F]FDG-PET scan were included. Linear regression analy...    »
 
Journal title abbreviation:
Neurobiol Aging 
Year:
2009 
Journal volume:
30 
Journal issue:
12 
Pages contribution:
1902-9 
Language:
eng 
Print-ISSN:
0197-4580 
TUM Institution:
r Psychiatrie und Psychotherapie; Nuklearmedizinische Klinik und Poliklinik