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Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Muñoz Javier, A; del Pino, P; Bedard, MF; Ho, D; Skirtach, AG; Sukhorukov, GB; Plank, C; Parak, WJ
Title:
Photoactivated release of cargo from the cavity of polyelectrolyte capsules to the cytosol of cells.
Abstract:
Polyelectrolyte capsules with metal nanoparticles in their walls and fluorescently labeled polymers as cargo inside their cavity were prepared. Capsules were ingested by living cells with no uncontrolled release of the cargo upon the incorporation process. Photoinduced heating of the metal nanoparticles in the capsule walls lead to rupture of the capsule walls, and the polymeric cargo was released to the whole cytosol. Viability tests demonstrate that opening of capsules at moderate light intens...     »
Journal title abbreviation:
Langmuir
Year:
2008
Journal volume:
24
Journal issue:
21
Pages contribution:
12517-20
Language:
eng
Fulltext / DOI:
doi:10.1021/la802448z
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18844388
Print-ISSN:
0743-7463
TUM Institution:
Institut für Experimentelle Onkologie und Therapieforschung
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