Loudness dependence of the auditory evoked N1/P2 component as an indicator of serotonergic dysfunction in patients with schizophrenia--a replication study.

Document type:: journal article
Author(s):: Juckel, G; Gudlowski, Y; Müller, D; Ozgürdal, S; Brüne, M; Gallinat, J; Frodl, T; Witthaus, H; Uhl, I; Wutzler, A; Pogarell, O; Mulert, C; Hegerl, U; Meisenzahl, EM
Title:: Loudness dependence of the auditory evoked N1/P2 component as an indicator of serotonergic dysfunction in patients with schizophrenia--a replication study.
Abstract:: Serotonergic dysfunction appears to be involved in the pathogenesis of schizophrenia. The loudness dependence of auditory evoked potentials (LDAEP) has been suggested to be a valid indicator of the brain serotonin system's activity in humans. Patients with schizophrenia showed weaker LDAEP, indicating high serotonergic activity, in comparison to healthy controls. Thus, we were able again to demonstrate electrophysiological evidence for an upregulated serotonergic system in schizophrenia.
Journal title abbreviation:: Psychiatry Res
Year:: 2008
Journal volume:: 158
Journal issue:: 1
Pages contribution:: 79-82
Language:: eng
Pubmed ID:: http://view.ncbi.nlm.nih.gov/pubmed/18096246
Print-ISSN:: 0165-1781
TUM Institution:: Institut für Radiologie
BibTeX

Occurrences: