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Document type:
journal article 
Author(s):
Sarid, L; Bruno, R; Sakmann, B; Segev, I; Feldmeyer, D 
Title:
Modeling a layer 4-to-layer 2/3 module of a single column in rat neocortex: interweaving in vitro and in vivo experimental observations. 
Abstract:
We report a step in constructing an in silico model of a neocortical column, focusing on the synaptic connection between layer 4 (L4) spiny neurons and L2/3 pyramidal cells in rat barrel cortex. It is based first on a detailed morphological and functional characterization of synaptically connected pairs of L4-L2/3 neurons from in vitro recordings and second, on in vivo recordings of voltage responses of L2/3 pyramidal cells to current pulses and to whisker deflection. In vitro data and a detaile...    »
 
Journal title abbreviation:
Proc Natl Acad Sci U S A 
Year:
2007 
Journal volume:
104 
Journal issue:
41 
Pages contribution:
16353-8 
Language:
eng 
Print-ISSN:
0027-8424 
TUM Institution:
Institut für Neurowissenschaften