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Document type:
journal article 
Author(s):
Kümmel, S; Eggemann, H; Lüftner, D; Gebauer, N; Bühler, H; Schaller, G; Schmid, P; Kreienberg, R; Emons, G; Kriner, M; Elling, D; Blohmer, JU; Thomas, A 
Title:
Significant changes in circulating plasma levels of IGF1 and IGFBP3 after conventional or dose-intensified adjuvant treatment of breast cancer patients with one to three positive lymph nodes. 
Abstract:
The insulin-like growth factor 1 (IGF1) and its binding protein IGFBP3 (insulin-like growth factor binding protein 3) play a pivotal role during the growth and development of tissues. The purpose of this study was to evaluate the influence of anthracycline- and taxane-containing adjuvant chemotherapy in breast cancer patients on the circulating plasma levels of IGF1 and its main binding protein, IGFBP3. This investigation was part of a prospective randomized phase III study in which breast cance...    »
 
Journal title abbreviation:
Int J Biol Markers 
Year:
2007 
Journal volume:
22 
Journal issue:
Pages contribution:
186-93 
Language:
eng 
Print-ISSN:
0393-6155 
TUM Institution:
Institut für Medizinische Statistik und Epidemiologie