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Document type:
journal article 
Author(s):
Wagner, KJ; Sprenger, T; Kochs, EF; Tölle, TR; Valet, M; Willoch, F 
Title:
Imaging Human Cerebral Pain Modulation by Dose-dependent Opioid Analgesia: A Positron Emission Tomography Activation Study Using Remifentanil. 
Abstract:
BACKGROUND:: Previous imaging studies have demonstrated a number of cortical and subcortical brain structures to be activated during noxious stimulation and infusion of narcotic analgesics. This study used O-water and positron emission tomography to investigate dose-dependent effects of the short-acting mu-selective opioid agonist remifentanil on regional cerebral blood flow during experimentally induced painful heat stimulation in healthy male volunteers. METHODS:: Positron emission tomography...    »
 
Journal title abbreviation:
Anesthesiology 
Year:
2007 
Journal volume:
106 
Journal issue:
Pages contribution:
548-556 
Language:
eng 
Print-ISSN:
0003-3022 
TUM Institution:
sthesiologie; Neurologische Klinik und Poliklinik