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Document type:
journal article 
Author(s):
Stolla, M; Pelisek, J; von Brühl, ML; Schäfer, A; Barocke, V; Heider, P; Lorenz, M; Tirniceriu, A; Steinhart, A; Bauersachs, J; Bray, PF; Massberg, S; Schulz, C 
Title:
Fractalkine is expressed in early and advanced atherosclerotic lesions and supports monocyte recruitment via CX3CR1. 
Abstract:
Fractalkine (CX3CL1, FKN) is expressed in the inflamed vascular wall and absence of FKN reduces atherogenesis. Whether FKN is expressed throughout all stages of atherosclerotic disease and whether it directly contributes to monocyte recruitment to atherosclerotic lesions is not known. We collected human atherosclerotic plaque material and blood samples from patients with carotid artery disease undergoing endarterectomy. Plaques were analyzed by immunohistochemistry and qPCR. We found that FKN is...    »
 
Journal title abbreviation:
PLoS ONE 
Year:
2012 
Journal volume:
Journal issue:
Pages contribution:
e43572 
Language:
eng 
TUM Institution:
Klinik für Herz- und Kreislauferkrankungen