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Document type:
journal article 
Author(s):
von Olshausen, Gesa; Quasdorff, Maria; Bester, Romina; Arzberger, Silke; Ko, Chunkyu; van de Klundert, Maarten; Zhang, Ke; Odenthal, Margarete; Ringelhan, Marc; Niessen, Carien M; Protzer, Ulrike 
Title:
Hepatitis B virus promotes ?-catenin-signalling and disassembly of adherens junctions in a Src kinase dependent fashion. 
Abstract:
Hepatitis B virus (HBV) infection is a prominent cause of hepatocellular carcinoma (HCC) but the underlying molecular mechanisms are complex and multiple pathways have been proposed such as the activation of the Wnt-/?-catenin-signalling and dysregulation of E-cadherin/?-catenin adherens junctions. This study aimed to identify mechanisms of how HBV infection and replication as well as HBV X protein (HBx) gene expression in the context of an HBV genome influence Wnt-/?-catenin-signalling and form...    »
 
Journal title abbreviation:
Oncotarget 
Year:
2018 
Journal volume:
Journal issue:
74 
Pages contribution:
33947-33960 
Language:
eng 
TUM Institution:
Institut für Virologie