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Document type:
journal article 
Author(s):
Giorgi, Carlotta; Marchi, Saverio; Simoes, Ines C M; Ren, Ziyu; Morciano, Giampaolo; Perrone, Mariasole; Patalas-Krawczyk, Paulina; Borchard, Sabine; J?drak, Paulina; Pierzynowska, Karolina; Szyma?ski, J?drzej; Wang, David Q; Portincasa, Piero; W?grzyn, Grzegorz; Zischka, Hans; Dobrzyn, Pawel; Bonora, Massimo; Duszynski, Jerzy; Rimessi, Alessandro; Karkucinska-Wieckowska, Agnieszka; Dobrzyn, Agnieszka; Szabadkai, Gyorgy; Zavan, Barbara; Oliveira, Paulo J; Sardao, Vilma A; Pinton, Paolo; Wieckows...    »
 
Title:
Mitochondria and Reactive Oxygen Species in Aging and Age-Related Diseases. 
Abstract:
Aging has been linked to several degenerative processes that, through the accumulation of molecular and cellular damage, can progressively lead to cell dysfunction and organ failure. Human aging is linked with a higher risk for individuals to develop cancer, neurodegenerative, cardiovascular, and metabolic disorders. The understanding of the molecular basis of aging and associated diseases has been one major challenge of scientific research over the last decades. Mitochondria, the center of oxid...    »
 
Journal title abbreviation:
Int Rev Cell Mol Biol 
Year:
2018 
Journal volume:
340 
Pages contribution:
209-344 
Language:
eng 
Print-ISSN:
1937-6448 
TUM Institution:
Institut für Toxikologie und Umwelthygiene