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Dokumenttyp:
journal article 
Autor(en):
Bissinger, Oliver; Probst, Florian Andreas; Wolff, Klaus-Dietrich; Jeschke, Anke; Weitz, Jochen; Deppe, Herbert; Kolk, Andreas 
Titel:
Comparative 3D micro-CT and 2D histomorphometry analysis of dental implant osseointegration in the maxilla of minipigs. 
Abstract:
The bone implant contact (BIC) has traditionally been evaluated with histological methods. Thereupon, strong correlations of two-dimensional (2D) BIC have been detected between ?CT and destructive histology. However, due to the high intra-sample variability in BIC values, one histological slice is not sufficient to represent 3D BIC. Therefore, our aim has been to correlate the averaged values of 3-4 histological sections to 3D ?CT.Fifty-four implants inserted into the maxilla of 14 minipigs were evaluated. Two different time points were selected to assess the 3D BIC (distance to implant: 2-5 voxels), an inner ring (6-30 voxels) and an outer ring (55-100 voxels) using ?CT (voxel size: 10 ?m) and to correlate the values to histomorphometry.Strong correlations (p< 0.0001; 28 days, 56 days, total) were seen between ?CT and histomorphometry concerning BIC (r = 0.84, r = 0.85, r = 0.83), the inner ring (r = 0.87, r = 0.87, r = 0.88) and the outer ring (r = 0.85, r = 0.85, r = 0.88). Closer to the implant, ?CT values were higher compared with histomorphometry.Although 3-4 histological slices per implant seem to predict the 3D BIC, ?CT might be advantageous because of its non-destructive 3D character. The healing time may not impact on the comparability. 
Zeitschriftentitel:
J Clin Periodontol 
Jahr:
2017 
Band / Volume:
44 
Heft / Issue:
Seitenangaben Beitrag:
418-427 
Sprache:
eng 
Print-ISSN:
0303-6979 
TUM Einrichtung:
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie