Abstract:
With its high-sensitivity, non-intrusive, and contactless measurement characteristics, laser-Doppler vibrometry (LDV) allows for a detailed insight into the vibrational dynamics of systems, regardless of their fragility and structural characteristics. This exploratory study investigates if and how LDV can be used for the mechanical characterization of transparent biological materials, such as hydrogels, living cells, and cellular aggregates, as well as native and engineered tissues.