In Silico and In Vitro Study towards the Rational Design of 4,4 -Disarylbisthiazoles as a Selective α-Synucleinopathy Biomarker

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Document type:: Zeitschriftenaufsatz
Author(s):: Uzuegbunam, Bright C. ; Li, Junhao ; Paslawski, Wojciech ; Weber, Wolfgang ; Svenningsson, Per ; Ågren, Hans ; Hooshyar Yousefi, Behrooz
Title:: In Silico and In Vitro Study towards the Rational Design of 4,4 -Disarylbisthiazoles as a Selective α-Synucleinopathy Biomarker
Keywords:: Article ; α-synuclein aggregates ; 4,4 -diarylbisthiazole ; binding affinity ; Hantzsch thiazole synthesis ; lipophilicity ; O-fluoroethylation ; O-fluoroPEGylation ; O-methylation
Journal title:: International Journal of Molecular Sciences
Year:: 2023
Journal volume:: 24
Journal issue:: 22
Fulltext / DOI:: doi:10.3390/ijms242216445
Publisher:: MDPI
E-ISSN:: 1422-0067
Date of publication:: 17.11.2023
CC license:: by, https://creativecommons.org/licenses/by/4.0

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