Xenon's Sedative Effect Is Mediated by Interaction with the Cyclic Nucleotide-Binding Domain (CNBD) of HCN2 Channels Expressed by Thalamocortical Neurons of the Ventrobasal Nucleus in Mice

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Document type:: Zeitschriftenaufsatz
Author(s):: Kassab, Nour El Dine ; Mehlfeld, Verena ; Kass, Jennifer ; Biel, Martin ; Schneider, Gerhard ; Rammes, Gerhard
Title:: Xenon's Sedative Effect Is Mediated by Interaction with the Cyclic Nucleotide-Binding Domain (CNBD) of HCN2 Channels Expressed by Thalamocortical Neurons of the Ventrobasal Nucleus in Mice
Keywords:: Article ; xenon ; anesthesia ; electrophysiology ; cyclic nucleotide-binding domain (CNBD) ; hyperpolarization-activated cyclic nucleotide-gated type-2 (HCN2) ; ventrobasal thalamus (VB) ; knocked-in hyperpolarization-activated cyclic nucleotide-gated type-2 mouse model ; cyclic adenosine monophosphate (cAMP)
Journal title:: International Journal of Molecular Sciences
Year:: 2023
Journal volume:: 24
Journal issue:: 10
Fulltext / DOI:: doi:10.3390/ijms24108613
Publisher:: MDPI
E-ISSN:: 1422-0067
Date of publication:: 11.05.2023
CC license:: by, https://creativecommons.org/licenses/by/4.0

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